本研究首次揭示BRD4通过调控Th17分化、吞噬作用等通路驱动日本血吸虫感染的肝脏炎症反应，其抑制剂JQ1可有效缓解肝组织损伤。该发现为理解天然抗性机制提供了新视角：东方田鼠通过早期激活BRD4通路快速清除寄生虫并终止炎症，而小鼠的延迟应答导致慢性病变。研究发表于《Parasites》时强调，靶向BRD4的辅助疗法有望与吡喹酮联用，同步实现病原清除与免疫病理控制，为血吸虫病治疗开辟新路径。

XIAMEN, July 6 (Xinhua) -- As morning sunlight danced on the shimmering Yundang Lake, Chen Kanglin jogged along the winding lakeside trail, while waterbirds gracefully skimmed past him. For Chen, the ...

A Chinese representative on Friday delivered a joint statement on behalf of more than 70 countries at the annual thematic panel discussion on technical cooperation and capacity-building, held ...