Viral-mediated Oct4 overexpression induces direct conversion of wildtype mammalian Müller glia to bipolar neurons, and this process is synergistically enhanced by loss of Notch signaling.

Presynaptic NMDA receptors can shape timing-dependent long-term depression in a way that departs from their classic postsynaptic role.

Life has been announced as a winner in the first Crossref Metadata Awards, recognising its commitment to high-quality ...

Resurrection of ancient forms of CD4 reveals how retroviruses have placed selective pressure on this gene in apes, acting to propagate infection-resistant alleles.

This important study provides insights into the role of maternal behavior in the learning and ontogeny of vocalization. It finds evidence that the maternal behavior of sac-winged bats (Saccopteryx ...

This valuable study focuses on defining how the HSP70 chaperone system utilizes J-domain proteins to regulate the heat shock response-associated transcription factor HSF1. Using a combination of ...

Efforts to estimate the reproducibility of published research results have focused on specific areas of research to date, such as cancer biology and psychology. The Brazilian Reproducibility ...

Yonk and colleagues provide a valuable, timely, and in-depth study showcasing the role of thalamostriatal inputs in learning and action selection. After characterizing the synaptic properties of these ...

This valuable study reports the conservation of sperm-egg envelope binding by demonstrating successful recognition of the micropyle in fish eggs by the mouse sperm. However, the evidence supporting ...