Objective Our previous studies have identified CXCL8 as the crucial chemokine responsible for gastric cancer metastasis mediated by loss of RACK1. However, the regulatory effect of CXCL8 on immune ...

a Academic Unit of Pathology, University of Leeds, Leeds, UK, b Centre for Digestive Diseases, General Infirmary at Leeds, Leeds, UK Professor M F Dixon, Academic Unit of Pathology, Algernon Firth ...

Department of Internal Medicine, Division of Gastroenterology, University Hospital Gasthuisberg, Leuven, Belgium Correspondence to: Professor S Vermeire Department of Internal Medicine, Division of ...

Introduction Granulomatosis with polyangiitis (GPA), formerly known as Wegener’s granulomatosis is an autoimmune necrotising granulomatous disorder affecting small to medium sized blood vessels mostly ...

The mechanisms underlying the chronic intestinal inflammation that is a hallmark of inflammatory bowel diseases (IBD) are complex. Components of the pathological response include the adaptive and ...

5 Integrated Cancer Prevention Center, Tel Aviv Medical Centre, affiliated to Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel Correspondence to Professor Nadir Arber, The Integrated ...

4 National Centre for Tropical Infectious Diseases, Haukeland University Hospital, Bergen, Norway 5 Department of Medicine, Unit for Infectious Diseases, Haukeland University Hospital, Bergen, Norway ...

1 Faculty of Health Sciences, The Shraga Segal Department of Microbiology and Immunology and The Cancer Research Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel 2 Department of ...

Objective Interleukin (IL)-36R signalling plays a proinflammatory role in different organs including the skin, but the expression of IL-36R ligands and their molecular function in intestinal ...

Correspondence to Brian B Scott, Department of Medicine, Lincoln County Hospital, Lincoln LN2 5QY, UK; drbbscott{at}aol.com Iron deficiency anaemia (IDA) occurs in 2–5% of adult men and postmenopausal ...

Background Despite the long-standing recommendations of high-protein diets for patients with cancer, the precise mechanisms of this dietary approach in benefiting tumour suppression and enhancing ...

Patients with ulcerative colitis (UC) are at increased risk of colorectal carcinoma. 1, 2 Many clinicians practice colonoscopic surveillance in these patients in the hope of detecting dysplasia or an ...