On the heels of a 1-5 homestand, the Mariners swept the series from San Diego Padres at Petco Park, doing something they haven't done since 2006.

The Seattle Mariners (25-19) and the San Diego Padres (27-17) wrap up a 3-game interleague series Sunday at Petco Park in San Diego. First pitch is scheduled for 4:10 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the Mariners vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Get San Diego vs Seattle baseball betting preview, spread and over/under insights for their matchup on May 18.

Evans used a steady diet of fastballs to keep the vaunted San Diego Padres ' lineup of heavy hitters off-stride. It worked as the Mariners posted a 5-1 win over the Padres at Petco Park. The young Mariners' prospect was able to not only pitch well, but he's been listening closely to the MLB pitching staff.

The Padres are favored at home (-170) against the Mariners (+143). The matchup on the mound for this contest is set with the San Diego Padres looking to Nick Pivetta (5-2), and Emerson Hancock (1-2) taking the ball for the Seattle Mariners.

Cal Raleigh led off the seventh inning with his 15th home run to break a tie, Dylan Moore had a two-run single in the ninth and the Seattle Mariners beat the San Diego Padres 4-1 on Saturday night.

Arkansas Travelers alum and current Seattle Mariners catcher Cal Raleigh made history after hitting his 15th home run of the season against the San Diego Padres on Saturday.

MLB player prop bets and odds for Julio Yamel Rodríguez on Sunday, May 18, 2025, as the Seattle Mariners take on the San Diego Padres.