Study approach The TRINITY study was a prospective diagnostic accuracy trial conducted at the Asian Institute of ...

This May, the World Health Assembly (WHA) will vote on re-establishing a mandate for the WHO to address the health ...

a Academic Unit of Pathology, University of Leeds, Leeds, UK, b Centre for Digestive Diseases, General Infirmary at Leeds, Leeds, UK Professor M F Dixon, Academic Unit of Pathology, Algernon Firth ...

Objective Our previous studies have identified CXCL8 as the crucial chemokine responsible for gastric cancer metastasis mediated by loss of RACK1. However, the regulatory effect of CXCL8 on immune ...

Gastroparesis is defined by delayed gastric emptying (GE) and symptoms of nausea, vomiting, bloating, postprandial fullness, early satiety and abdominal pain. Most common aetiologies include diabetes, ...

Background Despite the long-standing recommendations of high-protein diets for patients with cancer, the precise mechanisms of this dietary approach in benefiting tumour suppression and enhancing ...

Non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common chronic liver disease globally and is currently estimated to affect up to 38% of the global adult population. NAFLD is a ...

Introduction Granulomatosis with polyangiitis (GPA), formerly known as Wegener’s granulomatosis is an autoimmune necrotising granulomatous disorder affecting small to medium sized blood vessels mostly ...

Correspondence to Brian B Scott, Department of Medicine, Lincoln County Hospital, Lincoln LN2 5QY, UK; drbbscott{at}aol.com Iron deficiency anaemia (IDA) occurs in 2–5% of adult men and postmenopausal ...

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Background Inflammatory bowel diseases (IBDs) are characterised by dysbiosis and a leaky gut. The NADPH oxidase dual oxidase 2 (DUOX2) is upregulated in patients with IBD, yet its role in driving the ...

Faecal microbiota transplantation (FMT) has emerged as a transformative therapy for Clostridioides difficile infections and shows promise for various GI and systemic diseases. However, the poor ...