Objectives This longitudinal study compared emerging plasma biomarkers for neurodegenerative disease between controls, patients with Alzheimer’s disease (AD), Lewy body dementia (LBD), frontotemporal ...

Journal of Neurology, Neurosurgery and Psychiatry (JNNP)'s ambition is to publish the most ground-breaking and cutting-edge research from around the world. Encompassing the entire genre of ...

The Grey Walter Department of Clinical Neurophysiology, Frenchay Hospital, Bristol, UK Correspondence to: Dr Nick Kane The Grey Walter Department of Clinical Neurophysiology, Frenchay Hospital, ...

Parkinson’s disease and related disorders (PDRD) are the second most common neurodegenerative disease and a leading cause of death. However, patients with PDRD receive less end-of-life palliative care ...

Introduction The cerebellum has strong cortical and subcortical connectivity, but is rarely taken into account for clinical diagnosis in many neurodegenerative conditions, particularly in the absence ...

The National Hospital for Neurology and Neurosurgery, Queen Square and the Reta Lila Weston Institute of Neurological Studies, UCL, London, UK Correspondence to Professor Andrew Lees, Reta Lila Weston ...

Neurometabolic diseases are a group of individually rare but numerous and heterogeneous genetic diseases best known to paediatricians. The more recently reported adult forms may present with ...

Service d’Urgences Neurovasculaires, Hôpital Neurologique, Lyon, France and CREATIS, UMR CNRS 5515, Claude Bernard University, INSERM, Lyon, France Dr L Derex, Service d’Urgences Neurovasculaires, ...

Parkinson’s disease (PD) is an incurable and progressive neurological disorder leading to deleterious motor and non-motor consequences. Presently, no pharmacological agents can prevent PD evolution or ...

Objective Imaging is recommended to support the clinical diagnoses of dementias, yet imaging research studies rarely have pathological confirmation of disease. This study aims to characterise patterns ...

Objective Gait disturbance lowers activities of daily living in patients with Parkinson’s disease (PD) and related disorders. However, the effectiveness of pharmacological, surgical and rehabilitative ...

Correspondence to Dr Sameer A Sheth, Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA; Sameer.Sheth{at}bcm.edu Deep brain stimulation (DBS) is an established and growing ...