Antibody–siRNA conjugates (ARCs) are a type of promising drug modalities for cancer therapy. However, initial reports of ARCs present the gene knockdown effect only in limited tissues (e.g., muscles) ...

The rapid identification of respiratory virus outbreaks is needed to enable rational and effective public health interventions. We developed new quantitative approaches for simultaneous ...

Facilities operated by the US Department of Energy (DOE) are required to have extensive worker safety and health programs by regulation. We describe how Argonne National Laboratory (ANL) has ...

The ortho-nitrobenzyl (ONB) group is one of the most widely utilized photocages for spatiotemporal control of biological processes via the light-triggered activation of small molecules and ...

Chemistry of Materials Document Templates are available for preparing manuscripts for submission as well as for preparing final, accepted manuscripts. Authors are encouraged to use these templates for ...

The catalytic versatility of pentacoordinated iron is highlighted by the broad range of natural and engineered activities of heme enzymes such as cytochrome P450s, which position a porphyrin cofactor ...

Solar-powered interfacial evaporation is an emerging solar energy harvesting technology developed to address the global energy crisis and freshwater shortage. However, non-directionally flowing water ...

The development of efficient delivery systems for therapeutic agents with organ-specific targeting is critical for advancing targeted therapies for effective treatment. In this study, we present a ...

A concise, scalable total synthesis of (−)-bipinnatin J is disclosed. Commencing from inexpensive starting materials, this marine diterpenoid was fashioned through a convergent synthesis enabled by Ni ...

Plug flow has a huge chemical potential of charge separation at the solid−liquid interface not limited by the Debye length for effectively generating electricity via harvesting energy from rain.

Nickel-based electrocatalysts have been studied for the electrochemical 5-hydroxymethylfurfural oxidation reaction (HMFOR) to produce 2,5-furan-dicarboxylic acid. Their catalytic activity is suggested ...

Critical-sized bone defects present a clinical challenge due to their limited self-repair capacity. Application of bone tissue–engineering scaffolds often overlooks the dynamic modulation of the ...